Histamine intolerance affects millions of people every year, and many are unaware of its symptoms or that they may be presenting with it. The connective tissues in your body produce histamine to help organs, muscles, and nerves receive and deliver messages to your brain and immune system. For example, histamine signaling will trigger your brain tissues to release pent-up stomach acids to process the foods you eat. It also helps immune system response by drawing attention to damaged tissue that requires repair read more here