Graves disease is an autoimmune disorder of the thyroid gland resulting in an overproduction of thyroid hormone and is named after Robert Grave, an Irish doctor who described this thyrotoxicosis in 1835. The thyroid, being an endocrine gland that sits at the base on the neck, produces two important thyroid hormones, triiodothyronine (T3) and thyroxine (T4), which help us manage things like sleep, appetite, metabolism, energy, and heart rate.
The origins of Grave’s Disease is not known, but it is understood to be an autoimmune response. In Grave’s, the body improperly produces antibodies (referred to as thyrotropin receptor antibodies (TRAb) or thyroid-stimulating immunoglobulins (TSI) that cross-react with the cells of our thyroid, sending the thyroid into overdrive. The overproduction of thyroid hormone is referred to as hyperthyroidism read more here